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Published: 2020-06-15
Abstract Views: 191
Views PDF: 67
DOI: https://doi.org/10.53747/jnst.v10i2.34
Issue
Vol. 10 No. 2 (2020)
Section
Articles
How to Cite
Nguyen Ngoc, D. ., Dang Van, P. ., Le Anh, Q., Nguyen T. Kim, L., Nguyen Quoc, H., & Tran T. Thu, N. (2020). Study on the preparation of selenium nanoparticles by gamma Co-60 method and investigate the stability. Nuclear Science and Technology, 10(2), 26-31. https://doi.org/10.53747/jnst.v10i2.34

Study on the preparation of selenium nanoparticles by gamma Co-60 method and investigate the stability

Nguyen Ngoc Duy 1,2, Dang Van Phu 1, Le Anh Quoc 1, Nguyen T. Kim Lan 1, Nguyen Quoc Hien 1, Tran T. Thu Ngan 2
1 Research and Development Center for Radiation Technology, 202A, Street 11, Thu Duc District, Ho Chi Minh City, Vietnam
2 University of Science, VNU-HCM, 227 Nguyen Van Cu, District 5, Ho Chi Minh City, Vietnam

Main Article Content

Abstract

Among nanoparticle materials, selenium nanoparticles (SeNPs) have attracted wide spread attention due to their excellent bioavailability, high bioactivity and low toxicity compared to other ionic selenium compounds. SeNPs with size ~ 41.75 nm were synthesized by γ-irradiation method using oligochitosan (OC) as stabilizer. The prepared SeNPs/OC were characterized by UV-Vis spectroscopy and transmission electron microscope (TEM) images. The SeNPs/OC powder was also prepared by spray drying technique and the purity was verified by energy dispersive X-ray (EDX) analysis. The results of EDX showed that SeNPs/OC solution was of high purity. The stability of
SeNPs/OC solution was investigated. The results indicated that SeNPs/OC solution had good stability after 60 days of storage at 4ºC. At ambient temperature, the SeNPs/OC solution was unstable and agglomerated after about 15 days. The SeNPs/OC synthesized by γ-irradiation with the advantages of environmental friendly and mass production process may be potentially promising for applications in medicines, functional food and in other fields as well.

Article Details

Keywords

Selenium nanoparticles, γ-irradiation, oligochitosan

References

[1]. H.W. Tan, H.Y. Mo, A.T.Y. Lau, Y.M. Xu. “Selenium Species: Current Status and Potentials in Cancer Prevention and Therapy”, International Journal of Molecular Sciences, 20(1), 1-26, 2019.
[2]. S. Skalickova, V. Milosavljevic, K. Cihalova, et al. “Selenium nanoparticles as a nutrition supplement”, Nutrition, 33, 83-90, 2017.
[3]. J. Zhang, H. Wang, X. Yan, L. Zhang. “Comparison of short-term toxicity between nano-Se and selenite in mice”, Life Sciences, 76(10), 1099-1109, 2005.
[4]. J. Zhang, X. Wang, T. Xu. “Elemental selenium at nano size (nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with Se-methylselenocysteine in mice”, Toxicological Sciences, 101(1), 22-31, 2008.
[5]. X. Zhai, C. Zhang, G. Zhao, S. Stoll, F. Ren, X. Leng. “Antioxidant capacities of the selenium nanoparticles stabilized by chitosan”, Journal of nanobiotechnology, 15:4, 2017.
[6]. P. Sonkusre, R. Nanduri, P. Gupta, S.S. Cameotra. “Improved extraction of intracellular biogenic selenium nanoparticles and their specificity for cancer chemoprevention”, Journal of Nanomedicine & Nanotechnology, 5:2, 1000194, 2014.
[7]. E.N. Ali, S.M. El-Sonbaty, F.M. Salem. “Evaluation of selenium nanoparticles as a potential chemopreventive agent against lung carcinoma”, International Journal of Pharmaceutical Biological and ChemicalSciences, 2(4), 38-46, 2013.
[8]. E. Faghfuri, M.H. Yazdi, M. Mahdavi, Z. Sepehrizadeh, M.A. Faramarzi, F. Mavandadnejad, A.R. Shahverdi. “Dose-response relationship study of selenium nanoparticles as an immunostimulatory agent in cancer-bearing mice”, Archives of medical research, 46(1), 31-37, 2015.
[9]. Y. Zhu, Y. Qian, H. Huang, M. Zhang. “Preparation of nanometer-size selenium powders of uniform particle size by γ-irradiation”, Materials Letters, 28(1-3), 119-122, 1996.
[10]. N.Q. Hien, P.D. Tuan, D.V. Phu, L.A. Quoc, N.T.K. Lan, N.N. Duy, T.T. Hoa. “Gamma Co-60 ray irradiation synthesis of dextran stabilized selenium nanoparticles and their antioxidant activity”, Materials Chemistry and Physics, 205, 29-34, 2018.
[11]. Z.H. Lin, C.R.C. Wang. “Evidence on the size-dependent absorption spectral evolution of selenium nanoparticles”, Materials Chemistry and Physics, 92(2-3), 591-594, 2005.