Application of β-NMR to spectroscopy and imaging

Yutaka Mizoi1,2, Mototsugu Mihara3, Yoko Kimura3, Takato Sugisaki3, Gen Takayama3, Masaomi Tanaka4, Daiki Nishimura5, Yurika Otani3, Miki Fukutome3, Ryo Taguchi3, Chen Sitan3, Soshi Ishitani3, Rina Miyahara3, Kaoru Watanabe3, Mitsunori Fukuda3, Takuji Izumikawa6, Norihide Noguchi6, Kazuya Takatsu6, Hiroyuki Takahashi5, Asahi Yano7, Hibiki Seki8, Takashi Ohtsubo9, Kensaku Matsuta3, Atsushi Kitagawa9, Shinji Sato9
1 Osaka Electro-Communication University (OECU)
2 Open-It
3 Osaka University
4 RIKEN
5 Tokyo City University
6 Niigata University
7 University of Tsukuba
8 Saitama University
9 National Institute for Quantum and Radiological Science and Technology (QST)

Main Article Content

Abstract

Nuclear magnetic resonance (NMR) using β-decay radioisotopes, known as “β-NMR,” is used for research in nuclear physics. Recently, nuclear magnetic moments of β-decay radioisotopes have been precisely measured by β-NMR. Therefore, β-decay radioisotopes can be used for NMR spectroscopy in material sciences. Nuclei, whose spin is zero, such as 12C and 16O, cannot be used in conventional NMR. However, nonzero-spin radioactive isotopes of carbon and oxygen can be used in β-NMR. This advantage is powerful for investigating organic materials that cannot be investigated using conventional NMR. A technique is being developed to extend β-NMR for imaging use in magnetic resonance imaging (MRI). In this study, the imaging function was realized by installing β-ray tracking detectors in a β-NMR device. Nuclear-spin-polarized radioisotopes were injected into a sample, and β-rays were emitted from their positions. Consequently, one could track back β-ray source positions on the sample. These detectors were installed into a dipole magnet to observe the magnetic resonances. A radio frequency coil was installed surrounding the sample. By combining information about the β-ray tracks and magnetic resonances, it was possible to obtain NMR spectra and images. This method is called “β-MRI.” The system was evaluated, and its performances were estimated.

Article Details

Author Biographies

Yutaka Mizoi, Osaka Electro-Communication University (OECU), Open-It

18-8 Hatsucho Neyagawa, Osaka, 572-8530, Japan,

Mototsugu Mihara, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Yoko Kimura, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Takato Sugisaki, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Gen Takayama, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Masaomi Tanaka, RIKEN

2-1 Hirosawa Wako, Saitama, 351-0198, Japan,

Daiki Nishimura, Tokyo City University

1-28-1 Tamazutsumi Setagaya, Tokyo, 158-8557, Japan,

Yurika Otani, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Miki Fukutome, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Ryo Taguchi, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Chen Sitan, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan,

Soshi Ishitani, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Rina Miyahara, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Kaoru Watanabe, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Mitsunori Fukuda, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Takuji Izumikawa, Niigata University

8050 Ikarashi 2-no-cho Nishi-ku, Niigata, 950-2181, Japan

Norihide Noguchi, Niigata University

8050 Ikarashi 2-no-cho Nishi-ku, Niigata, 950-2181, Japan

Kazuya Takatsu, Niigata University

8050 Ikarashi 2-no-cho Nishi-ku, Niigata, 950-2181, Japan

Hiroyuki Takahashi, Tokyo City University

1-28-1 Tamazutsumi Setagaya, Tokyo, 158-8557, Japan

Asahi Yano, University of Tsukuba

1-1-1 Tennodai Tsukuba, Ibaraki, 305-8577, Japan

Hibiki Seki, Saitama University

255 Shimo-Okubo Sakura-ku Saitama, Saitama, 338-8570, Japan

Takashi Ohtsubo, National Institute for Quantum and Radiological Science and Technology (QST)

 

4-9-1 Anagawa Inage-ku Chiba, Chiba, 263-8555, Japan,

Kensaku Matsuta, Osaka University

1-1 Machikaneyama Toyonaka, Osaka, 560-0043, Japan

Atsushi Kitagawa, National Institute for Quantum and Radiological Science and Technology (QST)

 

4-9-1 Anagawa Inage-ku Chiba, Chiba, 263-8555, Japan

Shinji Sato, National Institute for Quantum and Radiological Science and Technology (QST)

 

4-9-1 Anagawa Inage-ku Chiba, Chiba, 263-8555, Japan,

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